Brian Dennehy Testifies re:Effect of Accutane on Co-Stars Health
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Brian Dennehy Testifies re:Effect of Accutane on Co-Stars Health

Thousand Oaks : CA : USA | Mar 12, 2011 at 1:07 PM PST
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Section of Film Gladiator Starring James Marshall and Cuba Gooding

Roche Holding AG(ROG) drug company was in court again dealing with a lawsuit over severe side effects from the use of Accutane. Actor Brian Dennehy testified on behalf of his former co-star James Marshall who was forced to abandon his promising acting career after emergency surgery to remove his colon. Marshall is bringing an $11 million suit against Roche, blaming the drug for his severe colitis. There have already been seven lawsuits for health damages found for the injured parties.

Rob Reiner also testified as to the limitless career options opening up for Marshall.

"Marshall had “this incredible sexuality and magnetism,” Reiner said in a videotaped deposition played for jurors yesterday. “He jumps off the screen and it’s rare. I thought, you know, here’s another James Dean. He blew me away.” Bloomberg

Roche withdrew its superstar drug from the US market in 2009 but the best information I can find for Canada is a Health Canada warning dated February 16, 2010 requiring Roche to add more caveats to its other warnings regarding Accutane. Until Accutane was withdrawn from the market, it was the second best performer for that Swiss drug company.

Accutane was sold in the US from 1982 until 2009. It is reported that approximately 16 million people worldwide took the drug to combat acne. Early on it was discovered that women, pregnant while taking Accutane had a higher than normal number of babies with birth defects. Women of childbearing age were warned away from the drug. Then reports of severe skin reactions in which the top layer of skin separated from the underlying layers started coming in. Some of the reactions were severe enough to lead to death. There was also anecdotal evidence that for some, Accutane use led to depression and suicide. Still the benefits for the majority were deemed to outweigh the risks.

Then a connection between Accutane and severe damage to the lining of the digestive tract was found. For some unfortunates the loss of the colon(bowel). That's the end of normal bowel movements. Two methods to deal with the loss of the colon are usually followed and are outlined in detail at the Crohns and Colitis Foundation of America

The generic name for Accutane is Isotretinoin. As if you didn't need another reason to shy away from dubious online drug suppliers, it was easy to find an internet supplier of Isotretinoin, no prescription necessary.

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Rising star James Marshall had his career cut short when he needed emergency surgery to remove his bowel. He claims that the injury resulted from the use of Accutane.
BMcPherson is based in Nanaimo, British Columbia, Canada, and is an Anchor on Allvoices.
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