Pick Your Real Madrid Team - Cristiano Ronaldo Out

Real Madrid are the only side in Europe’s major leagues to have won every competitive game since the season started. But that remarkable record will be put under the microscope against a rampant Sevilla side.

A number of injury concerns will force coach Manuel Pellegrini to reshuffle his team again, although the Chilean has already mastered the art of squad rotation.

Fernando Gago is the latest defensive midfielder to be hampered by injury, after picking up a muscle injury in Wednesday’s Champions League tie against Marseille. Lassana DiarraLassana Diarra, on the other hand, is on his way back from a shoulder niggle he sustained earlier in the week but Pellegrini has decided not to risk him and the Frenchman will thus remain in the Spanish capital.

Defenders Alvaro Arbeloa and Christoph Metzelder have also recovered from their respective knocks but the Spanish full-back has been deemed not fit enough to travel with the squad. Ruud van NistelrooyRuud van Nistelrooy is also sidelined.

The big news, unsurprisingly, concerns Cristiano RonaldoRonaldo. After a desperate race to recover from a sprained ankle, the Portuguese has failed to make the cut and this will be the first time since joining Los Merengues in the summer that he will miss a game in the famous white shirt.