US President Barack Obama is preparing to give a much-anticipated speech in Cairo, on the second leg of his tour of the Middle East and Europe.
Correspondents say the speech, aimed at young Arabs in the region, will avoid specific proposals but focus instead on improving US-Middle East relations.
Earlier, Mr Obama held talks in Riyadh with King Abdullah of Saudi Arabia.
Meanwhile, a new audio message said to be from al-Qaeda leader Osama Bin Laden has emerged, condemning Mr Obama.
The White House said the recording was an attempt to shift attention from Mr Obama's historic visit.
Barack Obama's Middle East tour is aimed at increasing US engagement with the Islamic world and overcoming misapprehensions on both sides.