And the Lord appeared unto him, and said, Go not down into Egypt; dwell in the land which I shall tell thee of:
-- Gen. 26:2 (KJV)
During this time of famine, the Lord appeared to Isaac for the purpose of guidance and direction. During tough times in life, seek God so that He will show you which direction that you need to go.
Numerical Analysis: The numerical pattern for this verse is 8,2,1,6. (8) Choose to have a new beginning in God so that He will meet with you. (2) To be delivered, listen to the voice of the Lord. (1) To follow God, do not go where He does not command for you to go. (6) To expose evil, realize that location is very important.