There will be four possible outcomes Amanda Knox could hear. Only one is in her favor.
Knox has been in prison for the past four years, serving a 26 year sentence for murder.
Whoever loses the appeal on Monday is expected to take the case to Italy's supreme court.
First, the Italian court could choose to uphold Knox's original conviction and order her to serve the remaining 22 years of her sentence in Italy. Knox, who was 20 when Kercher was killed and is 24 now, would be in jail until she is 47 if this is the outcome.
Second, the court could uphold the conviction and honor the prosecution's request to increase Knox's sentenceto life in prison, Italy's toughest sentence. This could include six months in daytime solitary confinement.
The court could also decide to uphold the conviction and reduce Knox's sentence.
The court could overturn her conviction and release her from prison. It would take a majority vote of the six jurors and two judges throw out the conviction. If they are evenly split, Knox and Sollecito will be free.